Information updates

New 2023 versions of ASCIA Action Plans for Anaphylaxis

ASCIA has developed new 2023 versions of ASCIA Action Plans for Anaphylaxis, to improve ease of use, which will be available from June 2023. This is the first major formatting change in 20 years, since ASCIA Action Plans for Anaphylaxis were first introduced in 2003. The plans can be accessed on the ASCIA website:

Whilst the signs of, and actions for anaphylaxis are unchanged, other updates have been made to improve ease of use:

  1. Patient specific details are all completed in the top section.* 
  2. Signs of, and actions for mild to moderate allergic reactions are in two easy to follow lists. 
  3. Instructions for adrenaline injectors are colour coded.
  4. Instructions for both adrenaline injectors are included in the General version of the plan.
  5. Device specific versions of the plan for Anapen® and EpiPen® include changes 1-3 listed above and a QR code which links to short animated videos with adrenaline injector instructions.

* This formatting may also facilitate use with some EMR systems, subject to approval by ASCIA.  

The format of the following plans have also been updated to be consistent with the 2023 versions of the red ASCIA Action Plan for Anaphylaxis:

  • ASCIA Action Plan for Allergic Reactions (green)
  • ASCIA Action Plan for Drug (Medication) Allergy (dark green)
  • ASCIA First Aid Plan for Anaphylaxis (orange)

 A summary of updates is available here.

pdfASCIA Action Plan for Anaphylaxis 2023 - What's New431.38 KB

pdfASCIA Action Plan Allergic Reactions 2023 - What's New321.66 KB

pdfASCIA Action Plan Drug Allergy 2023 - What's New338.87 KB

pdfASCIA First Aid Plan Anaphylaxis 2023 - What's New415.79 KB 

Updates will be made to ASCIA e-training courses in  July 2023. Previous versions of ASCIA Action Plans (2021 and 2022 versions) can still be used in 2023, as we expect that it will take around six  months to phase in the use of the new 2023 plans.

Suppliers of Anapen and EpiPen will be printing the new plans, for prescribers who prefer to complete a printed version.

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ASCIA Progress Report – National Allergy Council Projects  

Gap Analysis – Anaphylaxis and Allergy Training

ASCIA has progressed an extensive gap analysis to scope the current anaphylaxis and allergy training provided to undergraduate students in the education and healthcare sectors.

ASCIA will engage with relevant stakeholders to determine the benefits, enablers and barriers for incorporating anaphylaxis and allergy training into undergraduate courses.

Schools and Children’s Education/Care Services Project

  • A survey for people studying and/or working within the education industry (schools and children’s education/care services) has been developed to determine how anaphylaxis training is being provided in undergraduate education courses throughout Australia. This survey will be available to complete during June 2023 at
  • Data from three ASCIA anaphylaxis e-training courses for staff working in schools and children's education/care services is being analysed and compiled into reports. This feedback will help guide ASCIA to further improve the courses.

Shared Care for Allergy Project 

Surveys have been developed to determine the current anaphylaxis and allergy training in undergraduate health professional degrees and to evaluate ASCIA e-training courses for health professionals: 

  • Survey 1 in July 2023 for recent graduates to understand their undergraduate experience of anaphylaxis and allergy training.
  • Survey 2 in August 2023 for representatives from institutions.
  • Data from evaluation surveys for ASCIA anaphylaxis and allergy e-training courses for health professionals is also being analysed and a report will be developed to guide ASCIA to further improve the courses.

Reporting on Survey Results

The results of these surveys will be summarised in reports to:

  • Highlight factors influencing the decision to incorporate anaphylaxis and allergy training in undergraduate degrees.
  • Provide insights into the benefits of including anaphylaxis and allergy training for future educators and health professionals.
  • Outline potential improvements in ASCIA e-training courses based on feedback.
  • Provide feedback to assist in developing consistent minimum standards/competencies for anaphylaxis and allergy training across institutions.

Gap Analysis – Resource Management

A comprehensive review of the resources accessible to patients, carers and health professionals on the ASCIA website has been completed.  Each individual resource has been catalogued in a document that now forms an integral part of the collaborative gap analysis.

Promotion of Patient/Carer Support Organisations 

ASCIA Fast Facts are the first online resources for patients and carers that have been reviewed and updated in 2023 to ensure that plain language is used where possible and the following information is included at the start of each allergy document: For patient or carer support contact Allergy & Anaphylaxis Australia or Allergy New Zealand (including weblinks). The updated ASCIA Fast Facts on 20 topics will be online at in early June 2023.

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Registration is now open for ASCIA 2023 Conference

Registration is now open for the ASCIA 2023 Conference, to be held at the International Convention Centre (ICC) Sydney from Tuesday 5th to Friday 8th September 2023. This is a hybrid conference, which enables virtual registration for delegates who cannot attend in-person, and on-demand viewing of sessions for all registered delegates after the conference.

The ASCIA 2023 Conference Program Book is available here:


ASCIA 2023 Conference registration and abstract submission are now open:

Earlybird registration and abstract submission close on 4th July 2023.

Delegates may also wish to register for the following meetings that are being held during the ASCIA 2023 Conference week:

  • CIRCA meeting at the Garvan Institute, Darlinghurst on Monday 2nd September - Registration link TBC
  • Practical Rhinoscopy workshop at St Vincent’s Hospital, Darlinghurst on Saturday 9th September – Register here

The ASCIA 2023 Conference program includes current allergy and clinical immunology clinical issues and research findings, which will be presented by more than 60 speakers, including five international speakers - A/Prof Edmond Chan (Canada), Prof Anna Nowak-Wegrzyn (USA), Prof Anne Puel (France), Dr Lluis Quintana-Murc (France) and A/Prof Elizabeth Tham (Singapore).

The ASCIA 2023 Conference program will include main sessions from 9am to 6pm AEST each day, with a focus on:

  • Clinical Grand Rounds (CGR) Cases and selected Poster Presentations on Tuesday 5th September
  • Food Allergy and Anaphylaxis on Wednesday 6th September
  • Drug, Insect, Animal and Respiratory Allergy on Thursday 7th September
  • Immunodeficiency, Autoimmunity and Autoinflammatory Disorders on Friday 8th September

On Thursday 7th September an inaugural ASCIA Immunodeficiency Update for Nurses will be held.

On Friday 8th September there will be three concurrent Allergy Update meetings, which include some shared sessions:

  • ASCIA Allergy Update for Medical Practitioners
  • ASCIA Allergy Update for Nurses
  • ASCIA Allergy Update for Dietitians

To improve sustainability, the ASCIA 2023 Conference will feature:

  • A living, digital Program Book, which can be kept up to date and reduces waste associated with printing. 
  • Online posters, which reduces production costs and waste associated with printing and transporting of posters.
  • Namebadges that do not include a plastic holder and reusable lanyards.

The ASCIA 2023 Conference will provide an international standard of continuing professional development (CPD) for ASCIA members and other health professionals working in allergy and clinical immunology, as well as an opportunity for in-person interactions with colleagues.

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Outcomes from ASCIA Immunodeficiency Strategy Meeting

The ASCIA  Immunodeficiency Strategy for Australia and New Zealand meeting was held on Friday 28th April, to coincide with World Primary Immunodeficiency Week 2023. The meeting was attended by a range of stakeholders including clinicians (clinical immunologists, specialist nurses and allied health), patient/carer organisations (AusPIPs, IDFA and IDFNZ), and researchers. The meeting was supported by ASCIA and an unrestricted educational grant from CSL Behring. As a result of this meeting a list of proposed prioritised actions was developed which are outlined below,

We welcome feedback from ASCIA members and stakeholders on the following proposed prioritised actions:

1) Standards of care which includes care by GPs and other health professionals. (Goals 2, 3, 4, 5, 8)

An ASCIA Standards of Care for Inborn Errors of Immunity (IEI), also known as primary immunodeficiencies (PID), will be developed, which will assist in benchmarking and advocating for optimal services and treatment. The format will be similar to the Quality in Primary Immunodeficiency Services document, which was produced by the Royal College of Physicians in UK, but expanded to reflect the Australian and New Zealand situations.

2) Specific working groups, including genetic testing and newborn screening (NBS) clinical implementation. (Goals 1, 2, 3, 8)

ASCIA working groups will be formed to further address issues for better access and funding of genetic testing and the implementation of the clinical aspects for severe combined immunodeficiency (SCID) newborn screening (NBS). Whilst SCID NBS laboratory testing has been funded and commenced or will soon commence to cover all jurisdictions, each region has differences which need to be considered in a national approach for SCID NBS and genetic testing.

3) Education program for transition from paediatric to adult care and advocacy for resourcing of improved transition services based on the Standards of Care (Goal 4, 6)

It has been recognised that there are many aspects of transitioning from paediatric to adult services that should be improved for complex patients with IEI and their families  Programs addressing education and support for patients, families and service providers and advocacy for funding of appropriate supportive multidisclinary resources utilising the ASCIA Standards of Care for IEI will help address this.

4) Advocacy, including discussions regarding Chronic Disease Strategy, patient/carer support organisations, Rare Voices Australia, health economics, barriers to access and Indigenous Australian/Maori involving clinicians and patients. (Goals 4, 5, 8)

Advocacy will be central to many of our goals. The ASCIA Standards of Care document will be important, as will be collaborations with patient/carer support organisations and potential utilisation of the Chronic Disease Strategy.

5) Research initiatives, including an audit of access to testing/care and rejuvenation of ASCIA Immunodeficiency (ID) Register. (Goal 7)

An audit of access to testing and access to care was recommended, to better understand the inequities identified and the differences between access in public versus private heathcare systems.

Rejuvenation of the ASCIA Immunodeficiency (ID) Register is underway, but we need to optimise the entry of data, with recognition of the need for project officer support and the need to change from the existing waiver of consent to a formal consent process. An active ASCIA ID Register will allow documentation of numbers for advocacy and also allow expansion of research.

Why was the ASCIA Immunodeficiency Strategy initiated?

The ASCIA Immunodeficiency Strategy for Australia and New Zealand was established to address the needs of patients and their families affected by immunodeficiency in a targeted collaborative way. The development of the Strategy was built on the experience from the successful implementation of the National Allergy Strategy.

The first ASCIA Immunodeficiency Strategy meeting was held on Friday 8 March 2019 and was attended by a wide range of stakeholders including clinicians, patient/carer organisations and researchers. Despite the disruptions of the COVID pandemic over the last three years, there has been significant progress in some of these areas, but there are still substantial issues that need to be addressed.

The ASCIA Immunodeficiency Strategy for Australia and New Zealand document was developed from 2019-2021 and launched in April 2022. The Strategy includes eight goals to address key issues, as listed below. 

ASCIA Immunodeficiency Strategy Goals

Goal 1: Enable early diagnosis of severe combined immunodeficiency (SCID) by newborn screening

Goal 2: Enable early diagnosis of other PID/IEI disorders through recognition of early warning signs of PID/IEI disorders, appropriate testing and treatment.

Goal 3: Improve access to expert genetic diagnosis by using genomic and immune testing for patients with suspected or recently diagnosed PID/IEI disorders, or people with a family history of PID/IEI.

Goal 4: Ensure equitable access to specialist and multi-disciplinary care for patients with PID/IEI disorders, including those living in regional, rural and remote areas.

Goal 5: Ensure equitable access to treatments, that are appropriately supported and funded for patients with PID/IEI disorders.

Goal 6: Increase support for PID/IEI education and training for patients, carers and health professionals.

Goal 7: Increase support for multi-disciplinary clinical and laboratory PID/IEI research and collaborations.

Goal 8: Ensure that the priorities of Indigenous Australian and Maori populations are represented in PID/IEI diagnosis, care and research.

For more information about the Strategy visit

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World Primary Immunodeficiency Week 22-29 April 2023

To coincide with World Primary Immunodeficiency Week, 22-29 April and the  International Day of Immunology, 29 April 2023, ASCIA has issued the following media release, which is distributed by Lanham Media.

Media contact: Greg Townley | This email address is being protected from spambots. You need JavaScript enabled to view it. | 0414 195 908

AAP have covered the story on Friday 21 April which has been published by 60 outlets including Daily Mail, West Australian, Canberra Times and others:  Calls for national rules on genetic testing - The Canberra Times

Sydney Morning Herald also covered the story on Monday 24 April: Archie waited 32 years for a diagnosis. His nephew waited two months - Sydney Morning Herald

Urgent Need for Access to Genetic Testing for Immune Deficiencies

The Australian immunology community is united in urging policymakers and healthcare providers to ensure fair access to genomic testing for primary immunodeficiencies (PIs) in Australia. PIs are a group of over 400 rare and serious genetic disorders that significantly compromise the immune system's capacity to defend the body against infections and diseases. As a result, people with PIs are highly vulnerable to a wide range of infections and are at a heightened risk of having severe and life-threatening complications. This can lead to recurrent and persistent infections that can be difficult to treat, as well as an increased likelihood of developing serious health conditions.

Genomic testing is a type of medical testing that is used that examines a person's DNA to look for changes or variations that may cause or increase the risk of certain health conditions. This can help doctors diagnose and treat diseases, predict a person's risk of developing certain conditions, and personalise medical care.

Currently, specific children with cancer in Australia have access to in-depth genomic analysis through the Zero Childhood Cancer Program. The program's success in improving outcomes for these children has led to its expansion. This ability of early diagnosis is vital in people receiving precision treatment early in life.

The peak professional immunology and allergy organisation the Australasian Society of Clinical Immunology and Allergy (ASCIA), and patient/carer support organisations, Immune Deficiencies Foundation Australia (IDFA) and AusPIPS, are calling for a similar program to be established for people with PIs, who also require early and accurate diagnoses and targeted medical treatment.

“Unfortunately, access to genomic testing for primary immunodeficiencies is not currently equitable across Australia, which means that many people are not receiving the potentially life-saving care and treatment they need. It is truly devastating to lose patients, especially young ones, due to delayed diagnosis or the inability to control severe infections. We urge the Australian Government and state and territory governments to establish a jointly funded national genomics testing program, as recommended in the Parliamentary Inquiry into new drug and medical technology approval processes to ensure that genomic testing is accessible to all," says Dr Melanie Wong, a paediatric clinical immunology/allergy specialist and co-chair of the ASCIA Immunodeficiency Strategy.

Although individual cases of primary immunodeficiencies are uncommon, when considered collectively, they are estimated to affect 1 in 25,000 people. It is alarming to note that 70-90% of individuals with PI remain undiagnosed worldwide. In Australia (Victoria), research reveals that the average time taken for adults to receive a diagnosis after symptom onset is 8 years, and each year of delay in diagnosis results in a decrease in life expectancy.

54-year-old Pearl Sims, despite recurrent illness her whole life, was only diagnosed with Immunoglobulin G subclass deficiency at 31, which progressed to Common Variable Immunodeficiency (CVID) at age 41.

"I've been through so much because of my delayed diagnoses – missed school and work days, strained relationships, social isolation, and even the inability to have children of my own. It's been a constant struggle to fight for testing and a deeper understanding of my condition, and it breaks my heart to think that early detection could have made a huge difference. I firmly believe that knowledge is power, and genomic testing could have given me the answers I needed years ago, potentially sparing me from years of pain and missed opportunities. I also want to be able to provide information to my family for their own knowledge, but I am still on a long waitlist to get tested," says Ms Sims.

Carolyn Dews, CEO of IDFA, believes that access to genomic testing is vital for people living with PIs to enhance their quality of life and make meaningful contributions to society.

“Living with a PI can be incredibly challenging, with frequent hospitalisations, severe symptoms, and limited social interactions. This often leads to social isolation and mental health issues. Access to genomic testing will provide people with a chance to live a productive life free from the constraints of their illness,” says Ms Dews.

Genomic testing can help in the following ways:

  1. Accurate Diagnosis: Genomic testing can identify the genetic mutations that cause primary immunodeficiencies, which helps doctors accurately diagnose the specific type of PI a person has. This is important for selecting appropriate treatments and managing the condition.
  2. Family Screening: Genomic testing can identify if family members of an affected individual also carry the same genetic mutation, which can help with early diagnosis and treatment.
  3. Precision Medicine: Genomic testing can help doctors tailor treatment plans to an individual's specific genetic makeup. For example, some primary immunodeficiencies can be treated with gene therapy, which involves introducing a healthy copy of a mutated gene back into a person's cells. Genomic testing can identify the specific genetic mutation that needs to be targeted with gene therapy.
  4. Research and Development: Genomic testing can provide important insights into the underlying biology of primary immunodeficiencies, which can inform the development of new treatments and potential cures.

“Many people with immune deficiency experience a long journey, often years, between developing symptoms and obtaining a clear diagnosis. Genomic testing increases the speed and accuracy of diagnosis, thereby enabling targeted treatments that can greatly improve health and prevent complications. Genomic testing and interpretation for primary immune deficiency offers so much promise that it should be fairly available to all,” finished Professor Jo Douglass, clinical immunology/allergy specialist and co-chair of the ASCIA Immunodeficiency Strategy.

Available for interview:

  • Dr Melanie Wong (NSW) - paediatric clinical immunology/allergy specialist and co-chair of the ASCIA Immunodeficiency Strategy
  • Professor Jo Douglass (VIC) - clinical immunology/allergy specialist and co-chair of the ASCIA Immunodeficiency Strategy.
  • Carolyn Dews (NSW), CEO of Immune Deficiencies Foundation Australia (IDFA)
  • Associate Professor Theresa Cole (VIC) - ASCIA President and paediatric clinical immunology/allergy specialist 

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Updated ASCIA OIT for Food Allergy Position Paper

ASCIA Oral Immunotherapy (OIT) for Food Allergy Position Paper for health professionals has been updated in April 2023 and is available open access on the ASCIA website:

The ASCIA OIT for Food Allergy Position Paper includes the following current ASCIA recommendations for management of food allergy:

  • Currently, ASCIA does not recommend food OIT as a routine clinical treatment for patients with food allergy. For most patients, with the exception of patients with egg and milk allergy who tolerate those foods in baked forms, strict avoidance of confirmed food allergens remains the standard of care. This recommendation will remain in place until the long-term efficacy and safety of food OIT is optimised, and long-term patient-important and other clinically relevant outcomes are shown to be improved by OIT.
  • There remains potential for OIT to provide long term benefits for patients with food allergy. ASCIA strongly supports the provision of clinical trials to address this data gap and increased access to OIT in clinical trials for those patients and families who wish to undertake OIT.
  • While ASCIA recommends that food OIT should be undertaken in the context of a clinical trial, these opportunities may not always be available to patients. If food OIT is being considered outside of a clinical trial, ASCIA recommends a shared decision-making process with appropriate expert consultation and documentation of informed consent, and that OIT is provided under the supervision of a clinical immunology/allergy specialist, as part of a multidisciplinary team with expertise in food OIT. In these circumstances, ASCIA recommends that standardised measures of safety, effectiveness and patient-reported outcomes are collected to address the current gaps in knowledge.
  • If such therapy is undertaken, OIT should be performed using published peer reviewed treatment protocols. Dose increases must take place with qualified staff in a facility that has the necessary equipment to treat anaphylaxis. Prior to commencing OIT, a clinical diagnosis of allergy to the food in question must be established; a diagnosis cannot be based on skin tests or blood tests in isolation. A supervised oral food allergen challenge in an appropriate setting may be needed to confirm the diagnosis or to establish a reaction threshold.
  • Any patient receiving OIT should have an adrenaline injector available at all times. Comprehensive anaphylaxis education regarding the recognition and management of anaphylaxis should be provided for the patient and/or their carers and a written management plan should be provided. Clear written information about when to avoid a dose (for example, prior to exercise) should be provided.

This is an important ASCIA document which will next be reviewed and updated in 2024, once a systematic review on food allergy treatments is completed, which we expect will be in late 2023.

ASCIA OIT for Food Allergy Frequently Asked Questions (FAQ) for patients and carers is also available on the ASCIA website:

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Updated ASCIA IVIg Infusion Guidelines

ASCIA Intravenous Immunoglobulin (IVIg) Infusion Guidelines provide standardised infusion rates for both 5% and 10% IVIg solutions, regardless of product. These have been developed to avoid confusion, as individual IVIg products recommend different weight-based rates of infusion.

ASCIA IVIg Infusion Guidelines have been updated in April 2023 and are available at 

The updates include:

  • Details about Privigen AU® (CSL Behring), which will replace Intragam® 10 when it is phased out in 2023.
  • Details about Flebogamma® 10% (Grifols), Gamunex® (Grifols), Kiovig® (Takeda) and Octagam® 10%  (Octapharm).
  • Addition of ‘A reduction in maximum infusion rate may be required if post infusion symptoms such as headache or myalgia occur’ to the guide to follow when adverse reactions occur.
  • Amendment of 3 ml/kg/hour to 6 ml/kg/hour under ‘Subsequent Infusions’.

The rates that are recommended in the ASCIA Guidelines are generally well tolerated and are for patients with immune deficiency on replacement IVIg therapy. Patients using IVIg for other conditions such as Kawasaki disease or immunomodulation should follow local protocols.

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New ASCIA Penicillin Allergy FAQ

There are several types of penicillin antibiotics available, which are important for treating bacterial infections.

Many people are told that they have a penicillin allergy, or think that they have penicillin allergy, and are ‘labelled’ as having a penicillin allergy in their medical records. However, studies have shown that up to nine in ten of these people do not have a true penicillin allergy. Therefore, it is important to find out if you have a true penicillin allergy, so that you can receive the best treatment when you have a bacterial infection.

To answer the most frequently asked questions (FAQ) about penicillin allergy,  ASCIA Penicillin Allergy FAQ has been developed and is available at :

Being told that you have a penicillin allergy or thinking that you have a penicillin allergy when you do not have true penicillin allergy can mean that alternative antibiotics need to be used. These can result in longer treatment times, increased risk of side effects and higher healthcare costs.

If you have been labelled with a penicillin allergy, talk to your healthcare provider about being tested to find out if you have a true allergy. This information can help ensure that you receive the most effective and efficient treatment of bacterial infections.

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